Hi,
Yes you can do that based on lists and even specific newsletters. At least, to some extend. A mail is marked as opened when the user displays the images (note that many mail clients do not show images by defqault) or clicks on a link.
Go to "Automations" and create a mass action if you want to perform a manual action or creeate an automatiuon if you want to run it automaticly on certain times.
You'll see different tabs where you can set your conditions, targets and actions.